BME - Biomolecular Engineering

BME 5 Introduction to Biotechnology

Introduces the tools and applications of biotechnology in the fields of medicine, agriculture, the environment, and industry.

Credits

5

Instructor

The Staff, Wendy Rothwell, Nader Pourmand

General Education Code

PE-T

Quarter offered

Fall, Winter

BME 18 Scientific Principles of Life

The principles of life as it exists on this planet and how they generalize. Darwinian evolution, genomes, scientific theories of life (mechanistic, thermodynamic, information theoretic). Future of life: Internet, machine learning and adaptation, artificial intelligence, genome editing, fully artificial life. Earth Sciences 7 is recommended as preparation.

Credits

5

Instructor

David Haussler, David Deamer

General Education Code

SI

Quarter offered

Fall

BME 21L Introduction to Basic Laboratory Techniques

Introduces students to basic laboratory techniques that are essential to begin work in faculty research labs and on capstone projects. Students have several independent blocks/fixed projects and learn how to use various instruments and techniques employed in biotechnology laboratories, such as: calibration and use of the pipette; making up various buffers; pH titration; Bactrial transformation; TAcloning; plasmid and DNA isolation; Polymerase Chain Reaction (PCR); gel electrophoresis; Pyrosequencing; and an introduction to Linux for DNA sequence analysis. Students are billed a materials fee.

Credits

5

Instructor

Nader Pourmand

Requirements

Enrollment is restricted to bioengineering, bioinformatics, and biomolecular engineering and bioinformatics majors and proposed majors.

Quarter offered

Spring

BME 22L Foundations of Design and Experimentation in Molecular Biology, Part I

The first in a two-part series that includes BME 23L. Together these courses prepare bioengineering students for successful junior/senior year projects in faculty research laboratories, iGEM, or Senior Design. The focus is on molecular biology laboratory and introductory bioinformatics skills. Students will design and initiate an original metagenome study near the end of the term.

Credits

2

Instructor

M. Akeson

Requirements

Prerequisites: BME 21L and CHEM 1A, CHEM 1B, CHEM 1M, and CHEM 1N; or by permission of instructor. Enrollment is restricted to sophomores and juniors.

Quarter offered

Fall

BME 23L Foundations of Design and Experimentation in Molecular Biology, Part II

Continuation of BME 22L. Together these courses prepare bioengineering students for successful junior/senior year projects in faculty research laboratories, iGEM, or Senior Design. The focus is on molecular biology laboratory and introductory bioinformatics skills. Students will complete original metagenome and transcriptome studies.

Credits

2

Instructor

Akeson

Requirements

Prerequisites: BME 22L or by permission of instructor.

Quarter offered

Winter

BME 51A Applied Electronics for Bioengineers Part 1

Lab-based course that introduces measuring, modeling, and designing electronics circuits, emphasizing voltage dividers and complex impedance culminating in simple, negative-feedback op amp circuits for amplifying audio signals. Students are billed a materials fee.

Credits

5

Instructor

Kevin Karplus

Requirements

Prerequisite(s): MATH 19A; or MATH 11A by consent of instructor. High school physics recommended. Enrollment is restricted to bioengineering and biomolecular engineering & bioinformatics majors and proposed majors; other majors by consent.

Quarter offered

Winter

BME 51B Applied Electronics for Bioengineers Part 2

Lab-based course that introduces designing, measuring, and modeling electronics circuits, emphasizing RC filters and negative-feedback amplifiers for various sensors circuits for amplifying audio signals, design of multi-stage amplifiers, transimpedance amplifiers, instrumentation amplifiers, and class-D power amplifiers. Students are billed a materials fee.

Credits

5

Instructor

Kevin Karplus

Requirements

Prerequisite(s): BME 51A.

Quarter offered

Spring

BME 80G Bioethics in the 21st Century: Science, Business, and Society

Serves science and non-science majors interested in bioethics. Guest speakers and instructors lead discussions of major ethical questions having arisen from research in genetics, medicine, and industries supported by this knowledge.

Credits

5

Cross Listed Courses

PHIL 80G

General Education Code

PE-T

Quarter offered

Fall

BME 80H The Human Genome

Course will focus on understanding human genes. Accessible to non-science majors. Will cover principles of human inheritance and techniques used in gene analysis. The evolutionary, social, ethical, and legal issues associated with knowledge of the human genome will be discussed.

Credits

5

Instructor

The Staff, Wendy Rothwell

General Education Code

PE-T

Quarter offered

Winter, Spring, Summer

BME 94 Group Tutorial

Provides a means for a small group of students to study a particular topic in consultation with a faculty sponsor. Students submit petition to sponsoring agency.

Credits

5

Repeatable for credit

Yes

Quarter offered

Fall, Winter, Spring

BME 94F Group Tutorial

Provides a means for a small group of students to study a particular topic in consultation with a faculty sponsor. Students submit petition to sponsoring agency.

Credits

2

Repeatable for credit

Yes

Quarter offered

Fall, Winter, Spring

BME 99 Tutorial

Students submit petition to sponsoring agency.

Credits

5

Repeatable for credit

Yes

Quarter offered

Fall, Winter, Spring

BME 99F Tutorial

Students submit petition to sponsoring agency.

Credits

2

Repeatable for credit

Yes

Quarter offered

Fall, Winter, Spring

BME 105 Genetics in the Genomics Era

Principles of genetics and genomics focusing on how sequencing technologies enable us to understand gene function, genotype to phenotype relationships, and genetic inheritance.

Credits

5

Instructor

Angela Brooks

Requirements

Prerequisite(s): BIOL 20A and BIOE 20B. Enrollment is restricted to bioengineering, biomolecular engineering and bioinformatics, and bioinformatics majors and proposed majors.

Quarter offered

Spring

BME 110 Computational Biology Tools

Hands-on lectures and laboratory geared to teach basic tools and skills used in computational biology (genome browsers, sequence database searching, motif analysis, multiple sequence alignment, gene finders, phylogenetics analysis, protein structure visualization, and others). Web-based tools/databases are used on student laptops. Open to all science students; no prior programming or Unix experience required.

Credits

5

Instructor

The Staff, Todd Lowe, Angela Brooks, Russell Corbett-Detig, Daniel Kim

Requirements

Prerequisite(s): BME 105, or BIOL 100, or BIOL 105, or BIOC 100A, or CHEM 103, or declared Bioinformatics majors.

Quarter offered

Fall, Winter

BME 122H Extreme Environmental Virology

Examines life in extreme environments with an emphasis on the viruses that live there. Integrates aspects of virology, molecular biology, and computational biology. Students investigate a high-salt, extreme environment at the Don Edwards National Wildlife Refuge, and use DNA extraction methods to find molecular evidence of the organisms that live there and describe the genetic content of viruses and the community living in those high-salt ponds.

Credits

5

Instructor

The Staff, David Bernick

Requirements

Enrollment is restricted to College Scholar Students, and or by permission of the instructor.

General Education Code

TA

Quarter offered

Fall

BME 123T Senior Thesis Writing

For bioengineering senior thesis students, guidance in preparing a draft manuscript describing their senior research project. Students also practice conference-style oral or poster presentation. Enrollment is restricted to senior bioengineering majors.

Credits

5

Instructor

Kevin Karplus, Mark Akeson, Terry Terhaar

Requirements

Prerequisite(s): BME 185 or CSE 185E. Concurrent enrollment in BME 193F orBME 195F or BME 198F or CSE 193F or CSE 195F or CSE 198F or ECE 193F or ECE 195F or ECE 198F is required.

Quarter offered

Winter

BME 128 Protein Engineering

For bioengineering, bioinformatics, and biology majors, focuses on engineering (i.e., changing) of proteins. Topics focus on practical aspects of protein engineering strategies that are crucial to modern biotechnology and biomedicinal applications.

Credits

5

Instructor

The Staff, Rebecca Dubois

Requirements

Prerequisite(s): BIOL 20A; and BIOL 100 or BIOC 100A, or by permission of instructor.

Quarter offered

Winter

BME 128L Protein Engineering Laboratory

Students address a current scientific question about protein stability using structure-guided protein engineering. Specifically, Students use recombinant DNA technology to produce an engineered protein that is predicted to have enhanced stability. Students then assess its stability with differential scanning fluorimetry. Students are billed a materials fee.

Credits

2

Instructor

Rebecca Dubois

Requirements

Prerequisite(s): BIOC 100A or BIOL 100; and BIOL 101L, BIOL 20L, or BME 21L. Previous or concurrent enrollment in BME 128 is required. Enrollment is restricted to junior and senior bioengineering, bioinformatics, and biomolecular engineering and bioinformatics majors; other majors by permission of instructor.

Quarter offered

Spring

BME 129A Project Design and Implementation in Biomolecular Engineering I

First of a three-part series focused on senior design projects in biomolecular engineering. In this first part, students examine experiments that elucidated the function of biological macromolecules at the Angstrom scale, and how technologies related to those functions were invented and implemented. Guided by these examples, each student develops a senior design project concept or small business proposal and defends its utility, plausibility, and inventiveness in a written document and an oral presentation.

Credits

5

Instructor

Mark Akeson, Nader Pourmand

Requirements

Prerequisite(s): BIOL 20A and BIOL 20B; and BIOL 100 or BIOC 100A; BME 51A recommended. Enrollment is restricted to junior and senior bioengineering majors or by permission of the instructor.

Quarter offered

Fall

BME 129B Project Design and Implementation in Biomolecular Engineering II

Second part of a three-course sequence that is the culmination of the bioengineering program for students who chose a senior design group project to fulfill their capstone requirement. Students apply knowledge and skills gained in biomolecular engineering coursework to articulate, organize, and plan a senior design group project. Student groups complete research, specification, planning, and procurement for their project. Includes technical discussions, design reviews, and formal presentations. Students are billed a materials fee.

Credits

5

Instructor

M. Akeson, R. Corbett-Detig

Requirements

Prerequisite(s): BME 129A or BME 150. Enrollment is restricted to senior bioengineering majors.

Quarter offered

Winter

BME 129C Project Design and Implementation in Biomolecular Engineering III

Final part of a three-course sequence that is the culmination of the bioengineering program for students who chose a senior design group project to fulfill their capstone requirement. Students apply knowledge and skills gained in biomolecular engineering coursework to articulate, organize, and plan a senior design group project. Student groups complete research, specification, planning, and procurement for their project. Includes technical discussions, design reviews, and formal presentations. Students are billed a materials fee.

Credits

5

Instructor

Bernick, M. Akeson, D.

Requirements

Prerequisite(s): BME 129A and BME 129B. Enrollment is restricted to senior bioengineering majors.

General Education Code

PR-E

Quarter offered

Spring

BME 130 Genomes

Advanced elective for biology majors, examining biology on the genome scale. Topics include genome sequencing; large scale computational and functional analysis; features specific to prokaryotic, eukaryotic, or mammalian genomes; proteomics; SNP analysis; medical genomics; and genome evolution.

Credits

5

Instructor

Richard Edward Green

Requirements

Prerequisite(s): BIOL 100 or CHEM 103 or BIOC 100A; and BIOL 105 or BME 105; or approval of instructor.

Quarter offered

Fall

BME 132 Evolutionary Genomics

Covers major recent advances in evolutionary genomics. Students learn to analyze and interpret scientific writing in depth. Students also present on work covered in the class and produce one research or review paper. Students cannot receive credit for this courses and course 232.

Credits

5

Instructor

Russell Corbett-Detig

Requirements

Prerequisite(s): BME 105 or BIOL 105. Enrollment is restricted to juniors and seniors.

General Education Code

TA

Quarter offered

Fall

BME 140 Bioinstrumentation

Introduces the fundamental aspects of bioinstrumentation that are essential for beginning-level employment in clinical, pharmaceutical , and biotechnology laboratories. The advantages and disadvantages of several instruments are discussed and demonstrated, such as thermocycler, polymerase chain reaction (PCR), next-generation DNA sequencing platforms, pyrosequencing, fabless nanofabrication, ion-sensitive measurements, microarray fabrication, and fluorescent-activated cell sorter (FACS). Students are billed a materials fee.

Credits

5

Instructor

Nader Pourmand

Requirements

Prerequisite(s): BME 5; or BME 51A and BME 51B; or EE 101 and EE 101L; or BIOL 100; or BIOC 100A.

Quarter offered

Fall

BME 160 Research Programming in the Life Sciences

No programming experience is required, but basic computer and molecular biology understanding is assumed. Students learn programming in Python to manipulate biological data. Programming assignments comprise the majority of the assignments, and a final project using skills developed in this course is required. Lab section registration is required. BioPython and other modules introduced for use in the final project.

Credits

6

Instructor

The Staff, David Bernick, Joshua Stuart

Requirements

Prerequisite(s): BIOL 20A or BIOL 21A.

General Education Code

MF

Quarter offered

Winter, Spring

BME 163 Applied Visualization and Analysis of Scientific Data

Python and its Numpy, Scipy, and Matplotlib packages as well as Inkscape are used on scientific data to generate publication-quality figures. Students cannot receive credit for this course and course 263.

Credits

5

Instructor

Christopher Vollmers

Requirements

Prerequisite(s): BME 160 or BME 205. Prerequisites can be waived in cases where students have the required programming skills. Enrollment is restricted to juniors and seniors.

General Education Code

SR

Quarter offered

Spring

BME 175 Entrepreneurship in Biotechnology

Focuses on contemporary issues in commercializing biotechnology and genomics, emphasizing development of teamwork and communication skills. Topics include intellectual property management, fundraising, market analysis, and technology development as related to biotechnology start-ups. Students perform real-world tasks preparing for commercialization. Taught in conjunction with BME 275.

Credits

5

Instructor

Todd Lowe, Richard Edward Green

Quarter offered

Winter

BME 177 Engineering Stem Cells

For bioengineering students interested in stem cells. Class uses project-based learning to discuss basic stem cell concepts and past breakthrough approaches to identify and design solutions for technological hurdles in stem cell research.

Credits

5

Instructor

Shariati, C. Forsberg, D. Kim, A.

Requirements

Prerequisite(s): BME 140 or BME 150, and BIOL 100, or by consent of instructor.

General Education Code

TA

Quarter offered

Spring

BME 178 Stem Cell Biology

Basic concepts, experimental approaches, and therapeutic potential are discussed. Students gain experience in reading the primary scientific literature.

Credits

5

Instructor

Camilla Forsberg, Daniel Kim

Requirements

Prerequisite(s): BIOL 110; BIOL 115 recommended.

General Education Code

TA

Quarter offered

Winter

BME 180 Professional Practice in Bioengineering

Seminar course where students develop a research proposal and the collaborative skills needed for independent research projects. Includes professional practice development in collaboration skills, project management, proposal development, and funding.

Credits

2

Instructor

The Staff, David Bernick

Requirements

Prerequisite(s): previous or concurrent enrollment in BME 185 or CSE 185E. Enrollment is restricted to junior and senior bioengineering, biomolecular engineering and bioinformatics, and bioinformatics majors or by permission.

General Education Code

PR-E

Quarter offered

Winter

BME 185 Technical Writing for Biomolecular Engineers

Writing by biomolecular engineers, not to general audiences, but to engineers, engineering managers, and technical writers. Exercises include job application and resume, library puzzle, graphics, laboratory protocols, document specification, progress report, survey article or research proposal, poster, and oral presentation.

Credits

5

Instructor

Joy Hagen, Kevin Karplus

Requirements

Prerequisite(s): satisfaction of Entry Level Writing and Composition requirements; previous or concurrent enrollment in BIOL 20L or BIOL 101L. Enrollment restricted to junior and senior biomolecular engineering, bioengineering, and bioinformatics majors.

Quarter offered

Fall, Summer

BME 188A Synthetic Biology--Mentored Research A

Provides a multidisciplinary, collaborative research experience working on a project in synthetic biology. Working with one or more research faculty, student teams complete a substantial project. Multiple oral/written presentations are required, including a formal conference presentation. Prerequisite(s): course 180. Enrollment is restricted to juniors and seniors. Enrollment is by instructor permission.

Credits

5

Instructor

David Bernick

Repeatable for credit

Yes

Quarter offered

Spring

BME 188B Synthetic Biology--Mentored Research B

The second course in the two-quarter series in synthetic biology research. It continues the collaborative research endeavor that began in course 188A. Multiple oral/written presentations are required, including a formal conference presentation. Prerequisite(s): course 188A. Enrollment is restricted to juniors and seniors. Enrollment is by instructor permission.

Credits

5

Instructor

David Bernick

Repeatable for credit

Yes

Quarter offered

Summer

BME 193 Field Study

Provides for individual programs of study with specific aims and academic objectives carried out under the direction of a BME faculty member and a willing sponsor at a field site, using resources not normally available on campus. Credit is based upon written and oral presentations demonstrating the achievement of the objectives of the course. Students submit petition to sponsoring agency.

Credits

5

Repeatable for credit

Yes

Quarter offered

Fall, Winter, Spring

BME 193F Field Study

Provides for individual programs of study with specific aims and academic objectives carried out under the direction of a BME faculty member and a willing sponsor at a field site, using resources not normally available on campus. Credit is based upon written and oral presentations demonstrating the achievement of the objectives of the course. Students submit petition to sponsoring agency.

Credits

2

Repeatable for credit

Yes

Quarter offered

Fall, Winter, Spring

BME 194 Group Tutorial

A program of study arranged between a group of students and a faculty member. Students submit petition to sponsoring agency.

Credits

5

Repeatable for credit

Yes

Quarter offered

Fall, Winter, Spring

BME 194F Group Tutorial

A program of independent study arranged between a group of students and a faculty member. Students submit petition to sponsoring agency.

Credits

2

Repeatable for credit

Yes

Quarter offered

Fall, Winter, Spring

BME 195 Senior Thesis Research

Students submit petition to sponsoring agency.

Credits

5

Repeatable for credit

Yes

Quarter offered

Fall, Winter, Spring

BME 195F Senior Thesis or Research

Students submit petition to sponsoring agency.

Credits

2

Repeatable for credit

Yes

Quarter offered

Fall, Winter, Spring

BME 198 Individual Study or Research

Students submit petition to sponsoring agency.

Credits

5

Repeatable for credit

Yes

Quarter offered

Fall, Winter, Spring

BME 198F Individual Study or Research

Students submit petition to sponsoring agency.

Credits

2

Repeatable for credit

Yes

Quarter offered

Fall, Winter, Spring

BME 199 Tutorial

For fourth-year students majoring in bioinformatics or bioengineering.

Credits

5

Repeatable for credit

Yes

Quarter offered

Fall, Winter, Spring

BME 201 Scientific Writing

Covers effective writing styles for scientific communication for bio-science and engineering graduate students. Covers instruction for writing grant applications, scientific manuscripts, and thesis proposals. Students practice by preparing, editing, and evaluating each of these documents.

Credits

3

Instructor

R.E. Green, J. Stuart

Requirements

Enrollment is restricted to graduate students.

Quarter offered

Winter

BME 205 Bioinformatics Models and Algorithms

Covers bioinformatics models and algorithms: the use of computational techniques to convert the masses of information from biochemical experiments (DNA sequencing, DNA chips, and other high-throughput experimental methods) into useful information. Emphasis is on DNA and protein sequence alignment and analysis.

Credits

5

Instructor

The Staff, David Bernick, Kevin Karplus

Requirements

Enrollment is restricted to graduate students. Undergraduates may enroll with prerequisite(s): CSE 15; and CSE 107 or STAT 131; and BIOL 20A; and concurrent enrollment in BIOC 100A.

Quarter offered

Fall

BME 215 Applied Gene Technology

Detailed insight into the techniques and technological trends in genomics and transcriptomics, building the necessary foundations for further research in genetic association studies, population genetic association studies, population genetics, diagnostics, medicine, and drug development. Students should already have a deeper understanding of the basic tools of molecular biotechnology than acquired in introductory courses in biotechnology, biochemistry, and molecular biotechnology.

Credits

5

Instructor

Nader Pourmand

Requirements

Enrollment is restricted to graduate students.

BME 229 Protein and Cell Engineering

Focuses on established and novel strategies for protein and cell engineering. Explores concepts, design, and practical applications of engineered proteins, cells, and organisms as research tools and in therapeutic applications. Recommended for graduate students with interests in bioengineering.

Credits

5

Instructor

Camilla Forsberg, Rebecca Dubois

Requirements

Enrollment is restricted to graduate students. Undergraduates by permission of instructor.

BME 230A Introduction to Computational Genomics and Systems Biology

Introductory and intermediate-level topics in computational genomics, DNA and RNA sequence analysis, mapping, quantification, detection of variants and their associations with disease. Covers topics in machine-learning, probabilistic graphical models, gene regulatory network inference, and single cell analysis. Students conduct related independent research.

Credits

5

Instructor

Joshua Stuart, David Haussler, Benedict Paten

Requirements

Prerequisite(s): BME 205. Enrollment is restricted to juniors, seniors, and graduate students.

Quarter offered

Winter

BME 230B Advanced Computational Genomics and Systems Biology

Covers advanced topics in computational genomics, DNA and RNA sequence analysis, mapping, quantification, detection of variants and their associations with disease. Topics include machine-learning, probabilistic graphical models, gene regulatory network inference, and single cell analysis. Students participate in teams in a computational analysis competition.

Credits

5

Instructor

Joshua Stuart, David Haussler, Benedict Paten

Requirements

Prerequisite(s): BME 230A. Enrollment is restricted to juniors, seniors, and graduate students.

Quarter offered

Spring

BME 232 Evolutionary Genomics

Covers major recent advances in evolutionary genomics. Students learn to analyze and interpret scientific writing in depth. Students also present on work covered in the class and produce one research or review paper. Students may not receive credit for this course and course 132.

Credits

5

Instructor

Russell Corbett-Detig

Requirements

Enrollment is restricted to graduate students. BME 105 or BIOL 105 or equivalent courses in higher-level genetic processes are highly recommended.

Quarter offered

Fall

BME 237 Applied RNA Bioinformatics

Teaches methods for RNA gene discovery; gene expression quantification; probabalistic modeling, secondary structure/trans-interaction prediction; mRNA splicing; and functional analysis. Emphasis on leveraging comparative genomics and employing high-throughput RNA sequencing data. Includes lectures, scientific literature discussion, problem sets, and final gene-discovery project.

Credits

5

Instructor

The Staff, Todd Lowe, Angela Brooks

Requirements

Enrollment is restricted to seniors and graduate students.

Quarter offered

Spring

BME 263 Applied Visualization and Analysis of Scientific Data

Python and its Numpy, Scipy, and Matplotlib packages as well as Inkscape are used to generate publication quality figures from scientific data. Students cannot receive credit for this course and course 163.

Credits

5

Instructor

Christopher Vollmers

Requirements

Prerequisite(s): BME 160 or BME 205. Prerequisite(s) can be waived in cases where students have required programming skills. Enrollment is restricted to graduate students.

Quarter offered

Spring

BME 272 Precision Medicine

Focuses on modern "precision" approaches to understanding human health, where every patient is unique. Explores basic and clinical discoveries and 'omics-based medicine for the prevention, diagnosis, and treatment of disease. Emphasis is on genomic approaches and applications to cancer.

Credits

5

Instructor

D. Kim

Requirements

Enrollment restricted to juniors, seniors, and graduate students.

Quarter offered

Fall

BME 275 Entrepreneurship in Biotechnology

Focuses on contemporary issues in commercializing biotechnology and genomics, emphasizing development of teamwork and communication skills. Topics include intellectual property management, fundraising, market analysis, and technology development as related to biotechnology start-ups. Students perform real-world tasks preparing for commercialization. Taught in conjunction with Biomolecular Engineering 175.

Credits

5

Instructor

Todd Lowe, Richard Edward Green

Quarter offered

Winter

BME 280B Seminar on Bioinformatics and Bioengineering

Weekly seminar series covering topics of current research in computational biology, and bioinformatics. Current research work and literature in these areas are discussed.(Formerly Seminar on Bioinformatics.)

Credits

2

Instructor

C. Forsberg, J. Stuart, R.E. Green, A. Brooks, D. Kim

Repeatable for credit

Yes

Quarter offered

Fall, Winter, Spring

BME 281A Seminar on Processive Enzymes and Nanopores

Weekly seminar series covering experimental research in nanopore technology and single-molecule analysis of polymerase function. Current research work and literature is discussed. Students lead some discussions and participate in all meetings.

Credits

2

Instructor

Mark Akeson

Requirements

Enrollment is restricted to graduate students. Qualified undergraduates may enroll with permission of instructor.

Repeatable for credit

Yes

Quarter offered

Fall, Winter, Spring

BME 281C Seminar in Cancer Genomics

Presents current computational biology research to identify genomics-based signatures of cancer onset, progression, and treatment response. Examples of such investigations include: genetic pathway interpretation of multivariate high-throughput datasets; discovery of mutations in whole-genome sequence; identifications and quantification of gene isoforms, alleles, and copy number variants; and machine-learning tools to predict clinical outcomes. Students present their own research, host journal clubs, and attend lectures and teleconferences to learn about research conducted by national and international projects.

Credits

2

Instructor

Joshua Stuart, David Haussler

Requirements

Enrollment is restricted to graduate students.

Repeatable for credit

Yes

Quarter offered

Fall, Winter, Spring, Summer

BME 281D Seminar on Protein Engineering

Weekly seminar series covering experimental research in protein structure, function, and engineering. Current research work and literature in this area are discussed. Students lead some discussions and participate in all meetings.

Credits

2

Instructor

Rebecca Dubois

Requirements

Enrollment is restricted to graduate students.

Repeatable for credit

Yes

Quarter offered

Fall, Winter, Spring

BME 281E Seminar in Genomics

Current topics in genomics including high-throughput sequencing, genome assembly, and comparative genomics. Students design and implement independent research projects. Weekly laboratory meetings are held to discuss these projects and related research in the field.

Credits

2

Instructor

Richard Edward Green

Requirements

Enrollment is restricted to graduate students

Repeatable for credit

Yes

Quarter offered

Fall, Winter, Spring

BME 281F Blood Cell Development

Weekly seminar covering topics in current research on blood cell development and stem cell biology. Current research and literature in these areas discussed. Students lead some discussions and participate in all meetings.

Credits

2

Instructor

Camilla Forsberg

Requirements

Enrollment is restricted to graduate students. Undergraduates may enroll with permission of instructor.

Repeatable for credit

Yes

Quarter offered

Fall, Winter, Spring

BME 281H Seminar in Comparative Genomics

Weekly seminar series covering topics of current computational and experimental research in comparative genomics. Current research work and literature in this area discussed. Students lead some discussions and participate in all meetings.

Credits

2

Instructor

David Haussler

Requirements

Enrollment is restricted to graduate students; qualified undergraduates may enroll with permission of instructor.

Repeatable for credit

Yes

Quarter offered

Fall, Winter, Spring

BME 281J Seminar in Computational Genomics and Biomedicine

Research seminar of the UCSC Computational Genomic Laboratory and Platform Teams (cgl.genomics.ucsc.edu/). Topics include genomic and transcriptomic sequence analysis methods, comparative and evolutionary genomics, big-data genomic analysis, biomedical data sharing, and precision medicine.

Credits

2

Instructor

Benedict Paten

Requirements

Enrollment is restricted to graduate students.

Repeatable for credit

Yes

Quarter offered

Fall, Winter, Spring, Summer

BME 281L Seminar in Computational Genetics

Weekly seminar series covering topics and experimental research in computational genetics. Current research work and literature in this area discussed. Students lead some discussions and participate in all meetings.

Credits

2

Instructor

Todd Lowe

Requirements

Enrollment is restricted to graduate students; qualified undergraduates may enroll with permission of instructor.

Repeatable for credit

Yes

Quarter offered

Fall

BME 281N Seminar in Transcriptomics

Covers current topics in computational and experimental research in transcriptomics. Current research work and literature discussed. Weekly laboratory meetings held to discuss these projects and related research in the field.

Credits

2

Instructor

Angela Brooks

Requirements

Enrollment is restricted to graduate students.

Repeatable for credit

Yes

Quarter offered

Fall, Winter, Spring

BME 281P Seminar on Nanotechnology and Biosensors

Weekly seminar covering topics of research in the development of new tools and technologies to detect and study genes and proteins. Latest research work and literature in these areas are discussed. Students lead some discussions and participate in all meetings.

Credits

2

Instructor

Nader Pourmand

Requirements

Enrollment is restricted to graduate students; qualified undergraduates may enroll with permission of instructor.

Repeatable for credit

Yes

Quarter offered

Fall, Winter, Spring

BME 281R Seminar in Stem Cell Genomics

Weekly seminar series covering topics in research on stem cell genomics. Current research and literature in this area is discussed. Students lead some discussions and participate in all meetings.

Credits

2

Instructor

Daniel Kim

Requirements

Enrollment restricted to graduate students; qualified undergraduates may enroll with instructor permission.

Quarter offered

Fall, Winter, Spring

BME 281S Seminar in Computational Functional Genomics

Weekly seminar series covering topics of current computational and experimental research in computational functional genomics. Current research work and literature in this area discussed. Students lead some discussions and participate in all meetings.

Credits

2

Instructor

Joshua Stuart

Requirements

Enrollment is restricted to graduate students; qualified undergraduates may enroll with permission of instructor.

Repeatable for credit

Yes

Quarter offered

Fall, Winter, Spring

BME 281V Immunogenomics Seminar

Journal club and research presentations in immunogenomics. Enrollment is by consent of the instructor and is restricted to graduate students, juniors, and seniors.

Credits

2

Instructor

Christopher Vollmers

Repeatable for credit

Yes

Quarter offered

Fall, Winter, Spring

BME 281Z Seminar in Population and Evolutionary Genomics

Covers major recent topics in evolutionary and population genomics. Consists primarily of discussions of recent literature and updates on group members' research. Enrollment is available only to members of the Corbett-Detig laboratory.

Credits

2

Instructor

Russell Corbett-Detig

Repeatable for credit

Yes

Quarter offered

Fall, Winter, Spring

BME 293 Seminar in Biomolecular Engineering

Weekly seminar series covering topics of bioinformatics and biomolecular engineering research. Current research work and literature in this area discussed. Students lead some discussions and participate in all meetings.

Credits

5

Requirements

Enrollment is restricted to graduate students; qualified undergraduates may enroll with permission of instructor.

BME 296 Research in Bioinformatics

Independent research in bioinformatics under faculty supervision. Although this course may be repeated for credit, not every degree program accepts a repeated course towards degree requirements. Students submit petition to sponsoring agency.

Credits

5

Repeatable for credit

Yes

Quarter offered

Fall, Winter, Spring

BME 297A Independent Study or Research

Independent study or research under faculty supervision. Although course may be repeated for credit, not every degree program accepts a repeated course towards degree requirements. Students submit petition to sponsoring agency.

Credits

5

Repeatable for credit

Yes

Quarter offered

Fall

BME 297B Independent Study or Research

Independent study or research under faculty supervision. Although course may be repeated for credit, not every degree program accepts a repeated course towards degree requirements. Students submit petition to sponsoring agency.

Credits

10

Repeatable for credit

Yes

Quarter offered

Winter

BME 297C Independent Study or Research

Independent study or research under faculty supervision. Although course may be repeated for credit, not every degree program accepts a repeated course towards degree requirements. Students submit petition to sponsoring agency.

Credits

15

Repeatable for credit

Yes

Quarter offered

Spring

BME 297F Independent Study or Research

Independent study or research under faculty supervision. Although course may be repeated for credit, not every degree program accepts a repeated course towards degree requirements. Students submit petition to sponsoring agency. Enrollment is restricted to graduate students.

Credits

2

Repeatable for credit

Yes

Quarter offered

Fall, Winter, Spring

BME 299A Thesis Research

Thesis research conducted under faculty supervision. Although course may be repeated for credit, not every degree program accepts a repeated course towards degree requirements.Students submit petition to sponsoring agency.

Credits

5

Repeatable for credit

Yes

Quarter offered

Fall

BME 299B Thesis Research

Thesis research conducted under faculty supervision. Although course may be repeated for credit, not every degree program accepts a repeated course towards degree requirements.Students submit petition to sponsoring agency.

Credits

10

Repeatable for credit

Yes

Quarter offered

Winter

BME 299C Thesis Research

Thesis research conducted under faculty supervision. Although course may be repeated for credit, not every degree program accepts a repeated course towards degree requirements.Students submit petition to sponsoring agency.

Credits

15

Repeatable for credit

Yes

Quarter offered

Spring