Introduction
The Department of Microbiology and Environmental Toxicology (METX) focuses on the human and environmental health impacts of chemicals and pathogens. A unifying disciplinary theme of research in METX is that both environmental chemicals and pathogens represent physiological effects that, in many cases, elicit specific molecular and inflammatory responses that increase the risk of adverse health outcomes in exposed individuals. The METX Ph.D. program provides in-depth training in the human and environmental health impacts of chemicals and pathogens. We accomplish this goal through comprehensive coursework, extensive scientific communication training, and in-depth research culminating in a Ph.D. dissertation. Our training prepares students to become leaders in various fields, following career paths in academia, teaching, industry, and government.
Students typically graduate with a Ph.D. in four to six years.
Advancement to Candidacy
The student advances to candidacy after completing all coursework, completing the literature review (due beginning of fall quarter, second year), passing the Ph.D. qualifying examination (spring quarter, second year), and presenting a 50-minute departmental seminar (spring quarter, third year).
Course Requirements
Three required courses
| METX 200 | Interdisciplinary Approaches in Environmental Toxicology | 5 |
| METX 200B | Graduate Research Project Development | 5 |
| BIOL 289 | Practice of Science | 5 |
Students must take all three.
One science writing course
| METX 245A | Scientific Communication in Microbiology and Environmental Toxicology A | 5 |
| METX 205 | Scientific Grant Writing | 5 |
Students may select either course from this list.
One field specific core course
Students may select either course from this list.
At least one graduate-level elective
Students may select any graduate-level METX course from this list, or an approved course from another department.
| METX 201 | Sources and Fates of Pollutants | 5 |
| METX 210 | Molecular and Cellular Basis of Bacterial Pathogenesis | 5 |
| METX 238 | Pathogenesis: Molecular Mechanisms of Disease | 5 |
| METX 250 | Environmental Microbiology | 5 |
Students may elect to take both METX 202 and METX 206A to satisfy this requirement (i.e., one class counts as “field-specific," and the other counts as the “elective”). Students should contact the Graduate Advisory Committee (GAC) for approval on classes not listed here. The course must be a graduate level, 5-credit course.
Any additional courses recommended by their graduate advising committee.
Students will consult with their advising committee to determine if additional coursework is necessary for their success in the program.
Each quarter, all students (before and after advancement) must enroll in the following courses
The following classes may be taken as Satisfactory/Unsatisfactory (S/US) grading unless otherwise instructed by your graduate advisor.
METX Department Seminar
Research Units
Each quarter, students will consult with their advising committee or faculty advisor to determine which research course to enroll in.
Topical seminar associated with their thesis lab
Note: First-year students in the PBSE rotation program do not enroll in one of these until they have joined a permanent thesis lab.
| METX 281A | Seminar in Global Health | 2 |
| METX 281C | Topics in Environmental Microbiology | 2 |
| METX 281J | Mechanisms of Virulence and Resistance to Infectious Disease | 2 |
| METX 281M | Topics in Molecular Toxicology | 2 |
| METX 281O | Topics in Bacterial Pathogenesis | 2 |
| METX 281P | Origins and Applications of Human Gut Microbial Symbiosis | 2 |
| METX 281R | Topics in Genome-Environment Interactions | 2 |
| METX 281S | Cellular and Organismal Responses to Toxicants | 2 |
| METX 281V | Topics in Bacterial Pathogenesis and Innate Immunity | 2 |
| METX 281Y | Biofilms: Processes and Regulation | 2 |
Thesis Laboratory
Students may be admitted to the METX Ph.D. program as a “direct admit” or via the Ph.D. Program in Biomedical Sciences and Engineering (PBSE). Direct admits have an agreed upon thesis mentor at the time of admission and begin working in that lab immediately upon matriculation.
Students admitted via the PBSE graduate program are required to complete three rotations prior to identifying a thesis mentor/lab. At the end of each rotation, students must present on their rotation project either with a short talk or poster presentation. Rotations occur during fall and winter quarters. At the end of the third rotation, students identify an advisor to sponsor their thesis research, and typically begin in their thesis lab at the beginning of spring quarter. Students who are unable to secure a thesis laboratory after three rotations must contact the METX GAC to seek assistance in scheduling a possible fourth rotation, though this option is not guaranteed.
Regardless of rotation status, all students must secure an advisor to sponsor their thesis research by the end of their first academic year in order to remain in good standing.
Literature Review
Students are required to write a literature review summarizing the current state of the field of the proposed dissertation research. The review should be written with feedback from the student’s faculty advisor and is due to the student’s advisor and the program graduate advisor by the first day of fall quarter of the second year.
Qualifying Examination
Students will complete a Ph.D. qualifying examination (QE) comprised of both oral and written components. The QE must be completed by May 15 of the student's second year.
Department Seminar
Students must present a public seminar to the department each academic year. Most years, this seminar is a short talk (typically ~15 - 20 minutes). In the third year (prior to advancing to candidacy), students are required to give a full 50-minute seminar.
For first-year students in the PBSE rotation program, the required rotation talks satisfy this requirement. All other students, including first-year students not completing PBSE rotations (direct-admission to a lab) should give a talk during the regular METX departmental seminar series.
Teaching Requirement
Ph.D. students are required to work as a teaching assistant (TA) for at least one quarter. Fulfilling this requirement may happen pre or post candidacy.
Dissertation
Dissertation Reading Committee
All students must meet with an advisory committee at least once per year. Students meet with the METX Graduate Advisory Committee until they form their Dissertation Reading Committee (aka thesis committee) in Year 3.
Dissertation Reading Committee (DRC)
After advancing to candidacy, students must meet at least annually with their DRC in order to remain in good standing. Annual meetings must occur before the end of winter quarter each year. Students may be required to meet with their DRC more frequently to get additional feedback on their thesis research, or if dictated by their DRC or the Graduate Advisory Committee. The DRC remains standing until the student has completed all requirements for the doctoral degree.
Dissertation Submission and Defense
The student must submit their doctoral dissertation to their Dissertation Reading Committee (aka thesis committee) for tentative approval at least one month before presenting a formal, public doctoral research seminar and defending their thesis. Ph.D. students are expected to have at least one primary research article submitted prior to graduation.